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Write a draft introduction that includes at least the following 3 elements:
What do you know about the protein, Nucleolin? What are the known function(s) of this protein in general? Why are they important? Any diseases associated with mutations or malfunction of these proteins?
What is background of the biological problem involving nucleolin’s interaction with another protein or macromolecule that you have chosen to study? What is the hypothesis your study is designed to address?
What domains are present in nucleolin and the interacting protein? What are the structure-function relationships of these domain fold in terms of function and regulation? Any important biophysical features or characteristics? Which domains do you predict would be important for the interaction and why?
Note: Writing style – strictly scientific. Make sure you cite all the sources both within the text as well in the bibliography. I strongly encourage everyone to use any of the available free citation software (see resources) instead of manually typing in the references
A sample introduction is attached.
Due: June 30th, 2022 EOD
Grading Rubric:
1. Submitted on time (2 points)
2. Thorough review of the literature (5 points)
3. All 3 elements addressed (10 points)
4. Strictly scientific writing style (5 points)
5. Includes in-text citations as well as complete bibliography in a consistent citation style (3 points)
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