The skin growth data.

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QUESTION

As the junior research directors, your job is to interpret the skin growth data.  You are writing a report to the Vice-Presidents of Research and Marketing about the dermal toxicity of Psoriaskill and making a recommendation(s) for future research or marketing.  Follow standard scientific format for writing your report (introduction, methods, results, discussion/conclusion).

Your report MUST include the following information:

1a) Generate two different dose-response curves to graphically characterize the data.  Interpret the data in two different ways (having one graph with a log10 axis and graph with a non-logged axis does not count as two different graphs).  Explain briefly what each of the two graphs illustrates (1-2 sentences).

1b) EXCEPTION FOR GROUP OF 3: You will generate 3 different dose-response curves. The third dose response curve will reflect the data for Psoriaskill with the added ingredient Oxybenzone (which is by itself reported to cause some skin irritation effects in sensitive individuals).

2)  In your results section, identify:
A)  Threshold
B)  NOEL and LOEL (both if possible; if not, specify which and why only that metric)
C)  Approximate EC (effective concentration) 25, EC50, EC75

3)  In your GROUP discussion, interpret/answer the following:
A)  Are the values described above (parts 2 A-C) different for your two ways of interpreting the data?  Why or why not?
B)  Do you recommend continued development of this potion for psoriasis treatment?  Why or why not?

4)  At the end of the paper, include a break-down of who in the group did what (i.e., Diane wrote the introduction, Alex did the editing, etc.).

Also turn in an individual evaluation form (handed out separately) – it is for you to evaluate yourself and your partner.  This will be confidential so BE HONEST.  This will help us determine individual grades.

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