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Home » ***Please cite all information found and list in reference section*** 1) In your

***Please cite all information found and list in reference section*** 1) In your

    ***Please cite all information found and list in reference section***
    1) In your own words, define validation. (2 points)
    2) When is validation typically conducted by a laboratory? Discuss two instances in which a forensic laboratory should conduct a validation. (2 points)
    3) This course’s Module 1 reading material discussed the standards developing organization (SDO) responsible for approving and publishing forensic science standards, the Academy Standards Board (ASB). Locate the most recently approved American National Standards regarding:
    a) method validation for forensic toxicology
    b) method validation for forensic DNA
    List the standard’s name and number, the edition and date, and the standard’s direct web link for full credit. (2 points)
    4) Define: (2 points)
    a) Type A evaluation of uncertainty
    b) Type B evaluation of uncertainty
    5) You have been tasked with completing the validation for your forensic toxicology lab’s new method, which, once approved for use, will be used for quantitating a new synthetic drug, “XYZDZ”. You must first create a validation plan.
    a) List three items your validation plan should include. (3 points)
    b) Discuss two Type B sources of uncertainty that could be evaluated prior to validation in an effort to understand and/or limit their potential contributions toward measurement uncertainty. (2 points)
    c) Define and discuss three parameters that this quantitative method’s validation would require. (3 points)
    6) Why is it important for a laboratory conducting quantitative measurements to determine measurement uncertainty? (2 points)
    7) Why are there two types of validation for forensic DNA? (2 points)

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